Clinical Data

NYUMets_Brain de-identified clinical data is divided into three datasets with feature details viewable below:

  • Time Series Dataset - Each row in the time series dataset represents a point in time, in units of days indexed from each patient’s initial gamma knife radiosurgery. Dataset variables include clinical details related to medication changes, imaging timing/references to raw imaging files, procedure timing, clinical follow up, and outcomes.
  • Individual Dataset - Each row represents an individual patient with demographic details and summary clinical data.
  • Gamma Knife Details Dataset - Each row represents an individual gamma knife target to provide further details about available gamma knife radiosurgery.
  • Imaging Dataset Metadata - Each row represents a point in time with imaging.
  • NYUMets MONAI API - MONAI Extension for handling longitudinal oncology and imaging data.

Time Series Dataset

Variable Type Key Description
patient_identifier int
Randomly generated 8-digit identifier unique to each patient
visit_class int 1 = Medication
2 = Gamma Knife
3 = Image
4 = Follow Up
5 = Death 		Identifies type of visit corresponding to each row/point in time, each with distinct variables related to that event (color coded):
  • Medication event is an update to a patient's ordered medications
  • Gamma Knife indicates a gamma knife procedure
  • Image corresponds to a Brain MRI
  • Follow Up corresponds to an office appointment with associated clinical data from that visit
  • Death reports details related to a patient's death
time_from_gk_days int
Time indexed from initial gamma knife procedure in days
time_from_diagnosis_days int
Time indexed from primary cancer diagnosis in days
med_list_count int
Count of medication list events indexed from 1, per patient
medications string
List of medications at specified time point, comma-separated
image_id int
Randomly generated 10-digit identifier unique to each cranial imaging and corresponding to imaging dataset
image_count int
Count of cranial imaging events indexed from 1, per patient
image_available int 0 = No
1 = Yes 		Indicates whether associated raw imaging data is available in imaging dataset
gk_id int
Randomly generated 9-digit identifier unique to each gamma knife procedure, corresponding to gamma knife details dataset
gk_detail int 0 = No
1 = Yes 		Indicates whether specified gamma knife procedure has corresponding data in the gamma knife details dataset
gk_count int
Count of gamma knife procedures indexed from 1, per patient
total_vol_all_targets float
Volume in cubic centimeters of all gamma knife targets from procedure specified in that row
num_gk_targets int
Total number of targets from specified gamma knife plan
(note: target number may not be the same as number of tumors - a large irregular tumor could require multiple targets and multiple, nearby tumors could be captured by a single target)
total_num_tumors_gk int
Total number of tumors targeted by specified gamma knife plan
num_lobar_gk int
Number of tumors located in cerebrum targeted by specified gamma knife plan
num_brainstem_gk int
Number of tumors located in brainstem targeted by specified gamma knife plan
num_thal_bg_gk int
Number of tumors located in thalamus or basal ganglia targeted by specified gamma knife plan
num_cerebellum_gk int
Number of tumors located in cerebellum targeted by specified gamma knife plan
num_skull_gk int
Number of tumors located in the calvarium targeted by specified gamma knife plan
xdimension_largest float
Linear measurement in millimeters along x-axis of largest tumor in specified gamma knife plan
ydimension_largest float
Linear measurement in millimeters along y-axis of largest tumor in specified gamma knife plan
zdimension_largest float
Linear measurement in millimeters along z-axis of largest tumor in specified gamma knife plan
max_linear_dimension_largest float
Maximum linear measurement in millimeters along any dimension of largest tumor in specified gamma knife plan
target_volume_largest float
Volume of largest outlined target in cubic centimeters from specified gamma knife plan
planned_isodose_volume_largest float
Planed Isodose Volume (PIV) in cubic centimeters of the largest target from specified gamma knife plan
coverage_largest float
Proportion of outlined target covered in largest planned isodose volume from specified gamma knife plan
pci_largest float
Paddick Conformity Index (PCI) of the largest target from specified gamma knife plan
gri_largest float
Gradient index of the largest target from specified gamma knife plan
margin_dose_largest float
Margin dose in unit Gy of the largest target from specified gamma knife plan
percent_isodose_largest float
Prescription isodose line in percentage of the largest target from specified gamma knife plan
volume_12gy_largest float
Volume of tissue in cubic centimeters that received 12 Gy from the largest target of the specified gamma knife plan
num_isocenters_largest int
Number of isocenters used from the largest target of the specified gamma knife plan
max_dose float
Maximum dose in Gy from the largest target of the specified gamma knife plan
min_dose float
Minimum dose in Gy of the largest target of the specified gamma knife plan
mean_dose float
Mean dose in Gy within the largest target of the specified gamma knife plan
dose_rate float
Dose rate in Gy per minute of the specified gamma knife plan
beam_on_time float
Total beam on time in minutes of the specified gamma knife plan
repeat_gks int 0 = No
1 = Yes 		Indicates whether specified procedure is a repeat gamma knife procedure
kps_at_gks int
Karnofsky Performance Status (KPS) of patient at time of specified gamma knife procedure
boost_after_wbrt int 0 = No
1 = Yes 		Indicates whether specified gamma knife procedure was a boost of prior whole brain radiation therapt (WBRT)
hemorrhagic_tumor_any int 0 = No
1 = Yes 		Indicates whether any tumors treated at specified gamma knife procedure were hemorrhagic
resection_bed_included int 0 = No
1 = Yes 		Indicates whether any targets treated at specified gamma knife procedure were a resection bed of a recently resected tumor
anticonvulsants_at_gks int 0 = No
1 = Yes 		Indicates whether patient was on anticonvulsant medications at the time of the specified gamma knife procedure
num_srs_fractions int
Total number of fractions required for specified gamma knife plan
steroids_adjuvant int 0 = No
1 = Yes 		Indicates whether patient was on adjuvant steroids at the time of the specified gamma knife procedure
gk_imaging_type int 1 = MRI
2 = CT 		Indicates the type of cranial imaging used for gamma knife planning
treatment_day_complication int 0 = No complications
1 = Seizure
2 = Anesthesia-related complication
3 = GK unit dysfunction 		Indicates the type of complication, if any, that occured at the time of the specified gamma knife procedure
anesthesia_type int 1 = Conscious sedation
2 = local anesthetic
3 = general anesthesia 		Indicates the type of anesthetic used during the specified gamma knife procedure
fixation_type int 1 = Leksell Frame
2 = Mask
3 = Extend Frame 		Indicates the type of fixation applied during the specified gamma knife procedure
stereotaxis_defined_by int 1 = Fiducial markers
2 = Cone-based CT 		Indicates how stereotaxis targeting was determined during the specified gamma knife procedure
gamma_plan_used int 0 = No
1 = Yes 		Indicates whether radiosurgery plan was designed on program Gamma Plan during the specified gamma knife procedure
gamma_plan_algorithm int 1 = TMR10
2 = TMRClassic
3 = Convolution 		Indicates the type of algorithm used by Gamma Plan during the specified gamma knife procedure
follow_up_count int
Count of follow up visits indexed from 1, per patient
employment_status_fu int 1 = Unemployed
2 = Fully employed
3 = Partially employed		 Employment status at follow up visit
subseq_srs int 0 = No
1 = Yes 		Indicates patient underwent or was scheduled for upcoming repeat stereotactic radiosurgery around follow up visit
subseq_wbrt int 0 = No
1 = Yes 		Indicates patient underwent or was scheduled for upcoming whole brain radiation therapy around follow up visit
wbrt_dose int Dose of whole brain radiation therapy in unit Gy
wbrt_fractions int Number of fractions of whole brain radiation therapy
subseq_craniotomy int 0 = No
1 = Yes 		Indicates patient underwent or was scheduled for craniotomy around follow up visit
subseq_crani_reason int 1 = Tumor progression
2 = New metastasis
3 = Tumor hemorrhage 		Reason for craniotomy
subseq_chemo int 0 = No
1 = Yes 		Indicates patient underwent or was scheduled for chemotherapy around follow up visit
subseq_immuno int 0 = No
1 = Yes 		Indicates patient underwent or was scheduled for immunotherapy around follow up visit
num_tumors_treated_to_date int
Cumulative number of tumors treated at time of follow up visit
num_complete_response int
Number of tumors with a complete response at time of follow up visit
num_partial_response int
Number of tumors with a partial response at time of follow up visit
num_tumor_progress int
Number of tumors demonstrating tumor progression at time of follow up visit
num_tumor_hemorrhage int
Number of hemorrhagic tumors at time of follow up visit
new_metastases int 0 = No
1 = Yes 		Indicates if imaging at time of follow up visit demonstated new brain metastases
num_new_tumors int
Number of new brain metastases at time of follow up visit
change_tumor_fu int 1 = Smaller (complete response)
2 = Smaller (partial response)
3 = Stable
4 = Larger (growth)
5 = Larger (swelling) 		Radiographic change in tumor size at follow up of largest tumor
macdonaldcriteria int 1 = Complete response
2 = Partial response
3 = Stable
4 = Progression 		Tumor response based on MacDonald Criteria of the largest tumor
edema int 1 = Yes Indicates the presence of peritumoral edema on imaging at time of follow up visit
kps_fu int
Karnofsky Performance Status (KPS) of patient at time of follow up
ctcae_hearing int 0 = No related adverse event
1 = Grade 1 (mild)
2 = Grade 2 (moderate)
3 = Grade 3 (severe)
4 = Grade 4 (life-threatening)
5 = Grade 5 (death) 		Hearing loss with the number corresponding to a Grade from the Common Terminology Criteria for Adverse Events (CTCAE) to indicate severity
ctcae_cognitive int 0 = No related adverse event
1 = Grade 1 (mild)
2 = Grade 2 (moderate)
3 = Grade 3 (severe)
4 = Grade 4 (life-threatening)
5 = Grade 5 (death) 		Cognitive decline with the number corresponding to a Grade from the Common Terminology Criteria for Adverse Events (CTCAE) to indicate severity
ctcae_cns_necrosis int 0 = No related adverse event
1 = Grade 1 (mild)
2 = Grade 2 (moderate)
3 = Grade 3 (severe)
4 = Grade 4 (life-threatening)
5 = Grade 5 (death) 		CNS necrosis with the number corresponding to a Grade from the Common Terminology Criteria for Adverse Events (CTCAE) to indicate severity
ctcae_seizure int 0 = No related adverse event
1 = Grade 1 (mild)
2 = Grade 2 (moderate)
3 = Grade 3 (severe)
4 = Grade 4 (life-threatening)
5 = Grade 5 (death) 		Seizure with the number corresponding to a Grade from the Common Terminology Criteria for Adverse Events (CTCAE) to indicate severity
double_vision int 0 = No
1 = Yes 		Indicates whether patient had double vision at follow up visit
eq5d_mobility int 1 = I have no problems in walking about
2 = I have some problems in walking about
3 = I am confined to bed 		Response to mobility prompt on EQ-5D instrument at time of follow up visit
eq5d_selfcare int 1 = I have no problems with self-care
2 = I have some problems washing or dressing myself
3 = I am unable to wash or dress myself 		Response to self-care prompt on EQ-5D instrument at time of follow up visit
eq5d_usualactivities int 1 = I have no problems with performing my usual activities
2 = I have some problems with performing my usual activities
3 = I am unable to perform my usual activities 		Response to usual activites prompt on EQ-5D instrument at time of follow up visit
eq5d_pain int 1 = I have no pain or discomfort
2 = I have moderate pain or discomfort
3 = I have extreme pain or discomfort 		Response to pain/discomfort prompt on EQ-5D instrument at time of follow up visit
eq5d_anxiety int 1 = I am not anxious or depressed
2 = I am moderately anxious or depressed
3 = I am extremely anxious or depressed 		Response to anxiety/depression prompt on EQ-5D instrument at time of follow up visit
eq_vas_score int
Response to EQ-VAS to self report health between 100 (best imaginable health) and 0 (worst imaginable health) at time of follow up visit
facial_numbness_left int 0 = No
1 = Yes 		Indicates whether patient had left-sided facial numbness at time of follow up visit
facial_numbness_right int 0 = No
1 = Yes 		Indicates whether patient had right-sided facial numbness at time of follow up visit
vocal_cord_dysfunction int 0 = No
1 = Yes 		Indicates whether patient had vocal cord dysfunction at time of follow up visit
dysphagia int 0 = No
1 = Yes 		Indicates whether patient had dysphagia at time of follow up visit
visual_acuity_left int 0 = No
1 = Yes 		Indicates whether patient had decline in left eye visual acuity at time of follow up visit
visual_acuity_right int 0 = No
1 = Yes 		Indicates whether patient had decline in right eye visual acuity at time of follow up visit
tongue_weakness int 0 = No
1 = Yes 		Indicates whether patient had tongue weakness at time of follow up visit
gait_impairment int 0 = No
1 = Yes 		Indicates whether patient had gait impairment at time of follow up visit
sensory_deficit int 0 = No
1 = Yes 		Indicates whether patient had sensory deficit at time of follow up visit
neurostatus int 1 = Improved
2 = Stable
3 = Worse 		Reports relative change in neurological status at current follow up visit
anticonvulsant_use_fu int 0 = Not taking anticonvulsants
1 = Taking anticonvulsants 		Indicates whether patient is taking anticonvulsants at time of follow up visit
anticonvulsant_changes int 0 = Not taking
1 = Dose decreased
2 = Dose stable
3 = Dose increased 		Reports changes in anticonvulsant dosage at this visit
steroid_use_fu int 0 = Not taking steroids
1 = Taking steroids 		Indicates whether patient is taking steroids at time of follow up visit
death int 0 = alive
1 = death 		Indicates whether patient died at reported time
cause_of_death int 1 = Progression of brain metastases
2 = Systemic disease progression
3 = Other 		Reports cause of death if patient died
(note: The most common "other" were infection and pulmonary embolism)



Individual Dataset

Variable Type Key Description
patient_identifier int
Randomly generated 8-digit identifier unique to each patient
age_diagnosis int
Patient age at time of primary cancer diagnosis
total_fu_time int
Total amount of follow up time in days from initial gamma knife radiosurgery
tobacco_use_init int 0 = Never
1 = Former, quit more than one year before diagnosis
2 = Former, quit within one year of diagnosis
3 = Former, unknown quit time
4 = Current use 		Patient reported tobacco use at time of initial evaluation for gamma knife radiosurgery
smoking_pack_years int
Number of pack years if cigarette smoker
weight_init float
Patient weight in kilograms at initial evaluation for gamma knife radiosurgery
height_init float
Patient height in centimeters at initial evaluation for gamma knife radiosurgery
height_init float
Patient height in centimeters at initial evaluation for gamma knife radiosurgery
employment_init int 1 = Unemployed
2 = Fully employed
3 = Partially employed 		Patient employment status at initial evaluation for gamma knife radiosurgery
primary_histology int 1 = Lung cancer
2 = Melanoma
3 = Breast cancer
4 = Synovial sarcoma
5 = Gastrointestinal cancer
6 = Renal cell carcinoma
7 = Uterine cancer
8 = Ovarian cancer
9 = Pancreatic cancer
10 = Prostate cancer
11 = Bladder cancer
12 = Testicular cancer
13 = Lymphoma 		Primary cancer diagnosis
histol_confirmed int 0 = No
1 = Yes 		Indicates whether patient's primary cancer was histologically confirmed
extent_of_disease_init int 1 = Brain only
2 = Brain and primary
3 = Brain, primary, and one other metastatic location
4 = Brain, primary, and more than one metastatic location 		Extent of patient's disease at time of initial evaluation for gamma knife radiosurgery
site_earliest_met int 1 = Brain
2 = Liver
3 = Bone
4 = Lung
5 = Other 		Location of first identified metastatic lesion
extracranial_disease_status int 1 = Controlled
2 = Active 		Status of extracranial disease at time of initial evaluation for gamma knife radiosurgery
num_tumors_init int
Number of intracranial metastases at time of initial evaluation for gamma knife radiosurgery
prior_srs int 0 = No
1 = Yes 		Indicates whether patient had history of prior stereotactic radiosurgery before indexed initial gamma knife radiosurgery
days_srs_before_gk int
Time in days that patient had prior stereotactic radiosurgery before indexed initial gamma knife radiosurgery
prior_chemo int 0 = No
1 = Yes 		Indicates whether patient had chemotherapy before initial gamma knife radiosurgery
prior_immuno int 0 = No
1 = Yes 		Indicates whether patient had immunotherapy before initial gamma knife radiosurgery
prior_brain_surgery int 0 = No
1 = Yes 		Indicates whether patient had brain surgery before initial gamma knife radiosurgery
days_surg_before_gk int
Time in days that patient had prior brain surgery before initial gamma knife radiosurgery
prior_intracranial_hemorrhage int 0 = No
1 = Yes 		Indicates whether patient had intracranial hemorrhage before initial gamma knife radiosurgery
prior_extracranial_rad int 0 = No
1 = Yes 		Indicates whether patient had any extracranial radiation therapy before initial gamma knife radiosurgery
prior_wbrt int 0 = No
1 = Yes 		Indicates whether patient underwent whole brain radiation therapy (WBRT) before initial gamma knife radiosurgery
wbrt_dose float
Dose of whole brain radiation therapy (WBRT) in Gy if patient underwent WBRT prior to initial gamma knife radiosurgery
wbrt_fractions int
Number of fractions of whole brain radiation therapy (WBRT) if patient underwent WBRT prior to initial gamma knife radiosurgery
days_wbrt_before_gk int
Time in days that patient completed whole brain radiation therapy before initial gamma knife radiosurgery
rpa int 1 = Class 1: KPS >= 70,
< 65 years of age, controlled primary and no evidence of disease other than intracrnaial disease
2 = Class 2: All others not in class 1 or 3
3 = Class 3: KPS < 70 		Recursive partitioning analysis (RPA) of prognostic factors based on the classes developed by the Radiation Therapy Oncology Group (RTOG)groups
primary_diag_incidental int 0 = No
1 = Yes 		Indicates whether primary cancer diagnosis was found incidentally, without any presenting symptoms
primary_sym_headache int 0 = No
1 = Yes 		Indicates whether patient presented with headache when primary cancer diagnosis was determined
primary_sym_seizure int 0 = No
1 = Yes 		Indicates whether patient presented with a seizure when primary cancer diagnosis was determined
primary_sym_neurodef int 0 = No
1 = Yes 		Indicates whether patient presented with a neurological deficit when primary cancer diagnosis was determined
primary_sym_pain int 0 = No
1 = Yes 		Indicates whether patient presented with pain when primary cancer diagnosis was determined
primary_sym_bleeding int 0 = No
1 = Yes 		Indicates whether patient presented with bleeding when primary cancer diagnosis was determined
primary_sym_bleeding int 0 = No
1 = Yes 		Indicates whether patient presented with bleeding when primary cancer diagnosis was determined
primary_sym_other int 0 = No
1 = Yes 		Indicates whether patient presented with a different symptom when primary cancer diagnosis was determined
brain_diag_incidental int 0 = No
1 = Yes 		Indicates whether brain metastases were diagnosed incidentally, generally on screening imaging, without new symptoms
brain_pres_seizure int 0 = No
1 = Yes 		Indicates whether patient presented with a seizure when brain metastases were diagnosed
brain_pres_hemorrhage int 0 = No
1 = Yes 		Indicates whether patient presented with intracranial hemorrhage when brain metastases were diagnosed
brain_pres_neurodeficit int 0 = No
1 = Yes 		Indicates whether patient presented with a neurologic deficit when brain metastases were diagnosed
brain_pres_headache int 0 = No
1 = Yes 		Indicates whether patient presented with a headache when brain metastases were diagnosed
vision_impair_left int 0 = No
1 = Yes 		Indicates whether patient had decline in left eye visual acuity at time of initial evaluation for gamma knife radiosurgery
vision_impair_right int 0 = No
1 = Yes 		Indicates whether patient had decline in right eye visual acuity at time of initial evaluation for gamma knife radiosurgery
double_vision int 0 = No
1 = Yes 		Indicates whether patient had double vision at time of initial evaluation for gamma knife radiosurgery
facial_numb_left int 0 = No
1 = Yes 		Indicates whether patient had left-sided facial numbness at time of initial evaluation for gamma knife radiosurgery
facial_numb_right int 0 = No
1 = Yes 		Indicates whether patient had right-sided facial numbness at time of initial evaluation for gamma knife radiosurgery
dysphagia int 0 = No
1 = Yes 		Indicates whether patient had dysphagia at time of initial evaluation for gamma knife radiosurgery
vocal_cord_dysfunction int 0 = No
1 = Yes 		Indicates whether patient had vocal cord dysfunction at time of initial evaluation for gamma knife radiosurgery
nd_cranial_nerve int 0 = No
1 = Yes 		Indicates whether patient had any cranial nerve deficits at time of initial evaluation for gamma knife radiosurgery
cn1_deficit int 0 = No deficit
1 = Cranial nerve deficit 		Describes cranial nerve I deficit at time of initial evaluation for gamma knife radiosurgery
cn2_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve II deficit at time of initial evaluation for gamma knife radiosurgery
cn3_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve III deficit at time of initial evaluation for gamma knife radiosurgery
cn4_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve IV deficit at time of initial evaluation for gamma knife radiosurgery
cn5_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve V deficit at time of initial evaluation for gamma knife radiosurgery
cn6_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve VI deficit at time of initial evaluation for gamma knife radiosurgery
cn7_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve VII deficit at time of initial evaluation for gamma knife radiosurgery
cn8_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve VIII deficit at time of initial evaluation for gamma knife radiosurgery
cn9_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve IX deficit at time of initial evaluation for gamma knife radiosurgery
cn10_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve X deficit at time of initial evaluation for gamma knife radiosurgery
cn11_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve XI deficit at time of initial evaluation for gamma knife radiosurgery
cn12_deficit int 0 = None
1 = Unilateral
2 = Bilateral 		Describes cranial nerve XII deficit at time of initial evaluation for gamma knife radiosurgery
nd_sensory int 0 = No
1 = Yes 		Indicates if patient had any sensory neurologic deficits at time of initial evaluation for gamma knife radiosurgery
nd_tongue_weakness int 0 = No
1 = Yes 		Indicates if patient had tongue wekaness at time of initial evaluation for gamma knife radiosurgery
nd_gait int 0 = No
1 = Yes 		Indicates if patient had gait impairment at time of initial evaluation for gamma knife radiosurgery
nd_visual int 0 = No visual deficits
1 = Scotoma
2 = Quadrantanopsia
3 = Hemianopsia
4 = Blind (left)
5 = Bline (right) 		Describes visual deficits, if any, at time of initial evaluation for gamma knife radiosurgery
nd_motor int 0 = No motor deficits
1 = Monoparesis
2 = Monoplegia
3 = Hemiparesis
4 = Hemiplegia
Quadriparesis 		Describes motor deficits, if any, at time of initial evaluation for gamma knife radiosurgery
nd_balance int 0 = None
1 = Ataxia
2 = Dysmetria
3 = Mixed 		Describes balance impairments, if any, at time of initial evaluation for gamma knife radiosurgery
nd_concentration int 0 = No
1 = Yes 		Indicates if the patient had a decline in ability to concentrate at time of initial evaluation for gamma knife radiosurgery
nd_memory int 0 = No
1 = Yes 		Indicates if the patient had a decline in memory at time of initial evaluation for gamma knife radiosurgery
nd_othercognitive int 0 = No
1 = Yes 		Indicates if the patient had other cognitive deficits at time of initial evaluation for gamma knife radiosurgery
eq5d_mobility_init int 1 = I have no problems in walking about
2 = I have some problems in walking about
3 = I am confined to bed 		Response to mobility prompt on EQ-5D instrument at time of initial evaluation for gamma knife radiosurgery
eq5d_selfcare_init int 1 = I have no problems with self-care
2 = I have some problems washing or dressing myself
3 = I am unable to wash or dress myself 		Response to self-care prompt on EQ-5D instrument at time of initial evaluation for gamma knife radiosurgery
eq5d_usualactivities_init int 1 = I have no problems with performing my usual activities
2 = I have some problems with performing my usual activities
3 = I am unable to perform my usual activities 		Response to usual activites prompt on EQ-5D instrument at time of initial evaluation for gamma knife radiosurgery
eq5d_pain_init int 1 = I have no pain or discomfort
2 = I have moderate pain or discomfort
3 = I have extreme pain or discomfort 		Response to pain/discomfort prompt on EQ-5D instrument at time of initial evaluation for gamma knife radiosurgery
eq5d_anxiety_init int 1 = I am not anxious or depressed
2 = I am moderately anxious or depressed
3 = I am extremely anxious or depressed 		Response to anxiety/depression prompt on EQ-5D instrument at time of initial evaluation for gamma knife radiosurgery
eq_vas_score_init int
Response to EQ-VAS to self report health between 100 (best imaginable health) and 0 (worst imaginable health) at time of initial evaluation for gamma knife radiosurgery
images_count int
Total number of cranial imaging events
gk_count int
Total number of gamma knife procedures
total_vol_all_targets_all_gk float
Volume in cubic centimeters of gamma knife targets from all gamma knife procedures
total_num_tumors_all_gk int
Total number of tumors targeted in all gamma knife plans
num_lobar_all_gk int
Number of tumors located in cerebrum targeted in all gamma knife plans
num_brainstem_all_gk int
Number of tumors located in the brainstem targeted in all gamma knife plans
num_thal_bg_all_gk int
Number of tumors located in the thalamus or basal ganglia targeted in all gamma knife plans
num_cerebellum_all_gk int
Number of tumors located in cerebellum targeted in all gamma knife plans
num_skull_all_gk int
Number of tumors located in the calvarium targeted in all gamma knife plans
follow_up_count int
Total number of follow up visits
subseq_srs int 0 = No
1 = Yes 		Indicates if patient underwent repeat stereotactic radiosurgery after initial gamma knife radiosurgery
subseq_wbrt int 0 = No
1 = Yes 		Indicates if patient underwent whole brain radiation therapy after initial gamma knife radiosurgery
subseq_craniotomy int 0 = No
1 = Yes 		Indicates if patient underwent craniotomy after initial gamma knife radiosurgery
subseq_chemo int 0 = No
1 = Yes 		Indicates if patient underwent chemotherapy after initial gamma knife radiosurgery
subseq_immuno int 0 = No
1 = Yes 		Indicates if patient underwent immunotherapy after initial gamma knife radiosurgery
death int 0 = alive
1 = death 		Indicates whether patient died
days_to_death_from_gk int
Time in days after initial gamma knife radiosurgery until death
days_to_death_from_diag int
Time in days after primary cancer diagnosis until death
cause_of_death int 1 = Progression of brain metastases
2 = Systemic disease progression
3 = Other 		Reports cause of death if patient died



Gamma Knife Details Dataset

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Variable Type Key Description
patient_identifier int
Randomly generated 8-digit identifier unique to each patient
gk_id int
Randomly generated 9-digit identifier unique to each gamma knife procedure
days_after_initial_gk int
Time in days after initial gamma knife radiosurgery
gk_count int
Count of gamma knife procedures indexed from 1, per patient
target_count int
Count of gamma knife targets indexed from 1, per gamma knife plan
total_targets int
Total number of gamma knife targets of gamma knife plan
largest_target_in_plan int 0 = No
1 = Yes 		Indicates if target is largest in plan, corresponding to the represented target in the time series dataset
target_working_label string Label applied to individual target during planning to differentiate targets based on location
(note: These are working labels and no standard terminology or abbreviations applied)
target_volume float
Volume of outlined target in cubic centimeters
planned_isodose_volume float
Planed Isodose Volume (PIV) in cubic centimeters of the target
gtvpiv float
Gross target volume (GTV) in planned isodose volume (PIV)
pci float
Paddick Conformity Index (PCI) of the target
gri float
Gradient index of the target
margin_dose float
Margin dose in unit Gy of the target
percent_isodose float
Prescription isodose line in percentage for the target
volume_12gy float
Volume of tissue in cubic centimeters that received 12 Gy from target
max_dose float
Maximum dose in Gy from the target
beam_on_time float
Total beam on time in minutes of the specified gamma knife plan
total_vol_all_targets float
Total volume in cubic centimeters of all gamma knife targets from procedure